once called vitamin B-8 [1,2]. It is a lipotrophic
factor, a chelater, and seems to have positive effects
on the immune system [2,3]. It also shares many of
When it comes to moods, it basically helps people feel
better in various ways.
In healthy people, more
inositol is in the body than any other vitamin except
B-3. Inositol metabolism is sometimes
affected by diabetes, renal disease, respiratory
distress syndrome, multiple sclerosis, and
hypercholesterolemia. Inositol has been used as
nutritional support for people with brain, kidney, bone
marrow, skin, hair, mood, muscular control, and blood
cholesterol concerns. Inositol is involved with the
formation of phospholipids as well as cholesterol
metabolism. Inositol phospholipids are integral parts of
cellular and subcellular membranes and modulate many
enzymes including adenosine triphosphate (ATP).
Inositol has nutritional efficacy as a lipotrophic
factor and thus assists in burning hepatic and
intestinal triglycerides. Many diabetics have
lower inositol levels than non-diabetics; treatment with
dietary inositol has been shown to normalize neural
inositol levels, ATP activity, and motor conduction
velocities for diabetics. Recent reports suggest that
since inositol is a precursor of phophatidylinositol
biphosphate which is affected by certain noradrenalin
and serotonin receptors, it may be helpful for people
with depression, panic disorder, and
obsessive-compulsive disorder (OCD) at high levels .
Clinically, it is often recommended for OCD.
Web MD states, “Inositol is used for diabetic nerve
pain, panic disorder, high cholesterol, insomnia,
cancer, depression, schizophrenia, Alzheimer’s disease,
attention deficit-hyperactivity disorder (ADHD), autism,
promoting hair growth, a skin disorder called psoriasis,
and treating side effects of medical treatment with
lithium. Inositol is also used by mouth for
treating conditions associated with polycystic ovary
syndrome, including failure to ovulate; high blood
pressure; high triglycerides; and high levels of
The plant source inositol known as phytate  “has
strong chelating power for doubly charged metal ions”
and “is a putative antiproliferative agent and may have
antioxidant activity” . Thus, inositol in
Saccharomyces cerevisiae is preferred by some for its
Certain plant foods contain
phytate as well as myo-inositol.
“Myo-inositol may have antidepressant and
antianxiety activity…Myo-inositol has exhibited
positive effects in a number of studies related to
depression, panic attacks, and obsessive-compulsive
disorder…In general, it appears that myo-inositol may be
effective in many of the same disorders in which the
SSRIs have shown some usefulness” .
Inositol is also used clinically for ‘perfectionists’
and some with anger concerns.
The non-food version of inositol is made from phytin
processed with sulfuric acid . Inositol is a
lipotrophic factor, and is also necessary for hair
growth. While nutritional yeast is probably the best
source of inositol, it is also found in fruits,
lecithin, legumes, meats, milk, unrefined molasses,
raisins, vegetables, and whole grains .
Web MD states, “Inositol
might balance certain chemicals in the body to possibly
help with conditions such as panic disorder, depression,
obsessive-compulsive disorder, and polycystic ovary
syndrome” . In the body, inositol also has an
effect on calcium and magnesium levels , hence this
could explain some of the claimed results.“Inositol is
found in brewer’s yeast” . “Dosages range from
500 milligrams to 4 grams daily taken with meals” .
Nutrition from food, what a concept!
 Zeisel S. Choline.
In: Modern Nutrition in Health and Disease, 11th ed.
Wolters Kluwer| Lippincott Williams & Wilkins, 2012:
 Neumann C, ed. Serious
Nutrition. FR International, Canada, 2005
 Hendler SS, Rorvik DM.
PDR for Nutritional Supplements, 2nd edition.
Thomson Reuters, 2008, Montvale (NJ)
 Whelan WJ. What’s in a
Name? Vitamin B4. IUBMB Life, 57(2): 125, February
 Vera Reader. The assay of
vitamin B4. Biochem J. 1930; 24 (6):
 Castell LM, Burke LM,
Stears SJ, et al. A-Z of nutritional supplements:
dietary supplements, sports nutrition foods and
ergogenic aids for health and performance. Part 9. Br J
Sports Med. 2010;44(8):609-611
 Inositol. Web MD.
 Andlid TA, Veide J,
Sandberg AS. Metabolism of extracellular inositol
hexaphosphate (phytate) by Saccharomyces cerevisiae. Int
J. Food Microbiology. 2004;97(2):157-169
Manufacturing Guide: Nutrient Empowerment, volume 1.
Nutrition Resource, Lakeport (CA), 1986
 Balch JF, Balch PA.
Prescription for a Nutritional Healing, 2nd ed. Avery
Publishing, Garden City Park (NY), 1997
 Rudd RR, Shils M.
Magnesium. In Modern Nutrition in Health &
Disease, 10th ed. Lippincott Williams & Wilkins, 2006,
Some of these studies (or
citations) may not conform to peer review standards,
therefore, the results are not conclusive. Professionals
can, and often do, come to different conclusions when
reviewing scientific data. None
of these statements have been reviewed by the FDA.All
products distributed by Doctors’ Research, Inc. are
nutritional and are not intended for the treatment or
prevention of any medical condition.
B Stress Complex
Complete Ear Health
Smell & Taste
Green Vegetable Alkalyzer
High Stress Adrenal
Le Feminine Advantage
Omega 3 / EPA / DHA
Selenium E Complex
Serious Brain Enhancer
Vita B-6, B-12, & Folate
Wheat Germ Oil