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Serious Brain Enhancer TM

The human brain is a fascinating and complex organ. The brain is so complex that it is not possible that one or two isolated substances could possibly optimize nutrition for it. That is why Serious Brain Enhancer contains a combination of high nutrient foods and food extracts to provide some of the most complete and comprehensive support available anywhere. An optimally functioning brain is needed for an optimally functioning life. An optimally functioning brain has an excellent memory, can learn, can focus, is not depressed, and maintains proper mood. Note: Other than a wild salmon extract, all glandulars in this Food product are ovine from New Zealand.

Acerola Cherry is one of the most vitamin C dense Foods. Not only does it have free radical scavenging abilities, it also has been shown to increase the antioxidant abilities of some other foods (1).

"Alpha-Lipoic Acid, also known as thioctic acid"is a potent biological antioxidant" (2). Studies have concluded it helped aged mice improve memory (3), protects the brain from cerebral ischemia-induced reperfusion injury (4), that it counteracted glycollate-induced free radical toxicity (5), and that it had neuroprotective effects against ischemia (6). "Alpha lipoic acid is actually the most efficient way to help the body produce glutathione (7).

Choline is a required nutrient which is needed for the normal development of memory (8).

Corn Silk is normally used for the kidneys or liver (9), but appears to have synergistic properties for brain support.

Deoxyribonucleic acid (DNA), along with ribonucleic acid (RNA), act as "memorigenics" (10).

Eleuthero Root, once known as Siberian Ginseng, is an herbal adaptagen. "Siberian ginseng is used as a tonic for invigoration and fortification in times of fatigue and debility or declining capacity for work and concentration, and during convalescence" (9).

Flaxseeds contain 30-45% fatty oil--this oil consists primarily of linolenic acid (40-70%), linoleic acid (10-25%) and oleic acid (13-30%) (9). "Flaxseed oil can provide the body with ample quantities of the essential fatty acid omega 3, which is transmuted into another fatty acid and ultimately provides nourishment for the brain cells" (11).

Grape Seed Extract provides the richest source of oligomeric proanthocyanidins (OPCs) that is able to pass the blood brain barrier. Some consider OPCs an "anti-stroke" nutrient which "keeps collagen elastic and softens blood platelets" (11). OPCs have anti-oxidant effects (2); OPCs enhance the brain by encouraging vascular efficiency.

Inositol "can help alleviate anxiety by acting as a natural Valium minus the side effects" (11).

L-Carnosine has antiglycation effects and has been proposed as an "anti-aging drug" (12). Some believe it may be helpful to prevent complications associated with Alzheimer"s and other dementias (12).

L-Methionine is an essential sulfur amino acid which easily passes the blood-brain barrier where it is converted into S-adenosylmethionine (SAMe) (13). A study involving Parkinson"s found that it improved activity level, ease of movement, rigidity, mood, sleep, attention span, concentration, voice, and muscular strength (14).

L-Tyrosine has an effect on nerve impulse transmission and may "improve vigilance and lessen anxiety" (15)."Tyrosine and phenylalanine promote the production of dopamine within the brain, a vital compound responsible for regulating the operation of neurotransmitters" (11) (phenylalanine is naturally in ovine brain (16)).

"Lecithin is a type of lipid that is needed by every cell in the body"The protective sheaths surrounding the brain are composed of lecithin"Lecithin consists mostly of the B vitamin choline, and also contains linoleic acid and inositol" (17) in the forms of phosphatidylcholine and phosphatidylinositol. "This nutrient"improves brain function" (17). It also contains phosphatidylethanolamine.

OvineGlandulars products are a Food believed by their proponents to provide nutritional support for the corresponding gland in the body (18-21). Glandular organs have been apart of the human diet for centuries (22). Glandulars contain nutritional peptides, enzymes (when freeze or vacuumed-dried), and other tissue substances (18-21). Glandular substances may reduce aspects of cellular atrophy, degeneration, decreases in tissue elasticity, and other negative aspects associated with aging (21). Brain glandulars contain "specific brain cell activators" (23) and have been advised for slowness of thought, loss of memory, uncontrolled mental activity, nightmares, mental retardation, and epilepsy (24,25). A double-blind study involving bovine-brain derived phosphatidylserine found it was able to improve both behavior and cognition in elderly people with cognitive decline (26). "...phosphatidylserine enhances the ability of enzymes in membranes of nerve cells to relay messages in and out of the cells. This product can improve memory in older adults, and can ameliorate symptoms of depression" (11). Research suggests that the glandular source phosphatidylserine is more effective than soy isolate sources (27). Pituitary glandulars have been used for nearly a century to provide nutritional support for people with problems such as mental retardation, slowed growth, Down syndrome, epilepsy, loss of memory, developmentally delayed children, premature senility and other situations (23,28). Trachea naturally supplies chondroitin-sulfate A. Early research indicated that ruminant source glandulars (bovine, ovine) were better for humans than animal sources (21,29). Ovine brain tissue naturally contains about 1.0% methionine, 2.4% phenylalanine, .5% tryptophan and 1.8% tyrosine by dry weight (16); other ovine glands have a similar amino acid profile.

Selenium in Food has been found to be about twice as well retained as other forms (30).

Vitamin B6 deficiencies of vitamin B6 can eventually lead to symptomatic memory problems (11). Higher plasma levels of vitamin B6 do seem to correlate to better memory in the elderly (31). Even children with learning problems have been reported to respond to vitamin B6 (11). Vitamin B12 can prevent certain dementias and assist mood (2,32,33). Vitamins B6, B12, and folate all appear to assist memory function (2,11,32,33).

Vitamin E in Food has about 4.0 times the free radical scavenging strength of synthetic, non-food vitamin E (34). Vitamin E has antioxidant abilities and appears to have positive effects on preventing certain forms of cognitive decline (2,33). Food Vitamin E has been proven to have 12 micro moles per gram T.E. of lipophilic ORAC (oxygen radical absorbance capacity) [34]"ORAC is essentially a measurement of the ability to quench free radicals (antioxidant ability). It is interesting to note that so-called "natural" forms (like succinate) such as do not even work like Food Vitamin E"Even the PDR notes, "d-Alpha-Tocopherol succinate itself has no antioxidant activity" [35], so why would anyone want that for their vitamin E supplement?

It is no wonder, once they know the science, that doctors interested in optimal natural health recommend Food Serious Brain Enhancer as the preferred Food source for comprehensive brain nutrition.

 

Unlike many so-called "natural" formulas, Serious Brain Enhancer is only comprised of foods, contains no synthetic USP vitamins or isolated mineral salts, but only contains foods, food concemtrates, and food extracts.

Numerous university studies have concluded that supplements containing food nutrients are better than USP isolates. Food nutrients are better because they contain important enzymes, peptides, and phytonutrients CRITICAL to the UTILIZATION of vitamins and minerals which are not present in isolated USP nutrients. Published research has concluded that food vitamins are superior synthetic/USP vitamins.

Suggested use: 1-9 capsules per day or as recommended by your health care professional. Adjust usage according to nutritional lifestyle requirements.

REFERENCES

  1. Hwang J, Hodis HN, Sevanian A. Soy and alfalfa phytoestrogen extracts become potent low-density lipoprotein antioxidants in the presence of acerola cherry extract. J Agric Food Chem. 2001;49(1):308-314

  2. Sheldon S, Rorvik D, eds. PDR for Nutritional Supplements. Medical Economics, Montvale (NJ), 2001

  3. Stoll S, et al. The potent free radical scavenger alpha-lipoic acid improves memory in aged mice. Pharmacol Biochem Behav, 46(4):799-805, 1993

  4. Panigrahi M, et al. Alpha-lipoic acid protects against reperfusion injury following cerebral ischemia in rats. Brain Res, 717(1-2):184-188, 1996

  5. Sumathi R, et al. Effect of DL alpha-lipoic acid on tissue lipid peroxidation and antioxidant systems in normal and glycollate treated rats. Pharmacol Res, 27(4):309-318, 1993

  6. Cao X, Phillis JW. The free radical scavenger alpha-lipoic acid, protects against cerebral ischemia-referfusion injury in gerbils. Free Radical Res, 23(4):365-370, 1995

  7. Balch J. The hidden epidemic. Healthy Living, 32:1-7, 2000

  8. Zeisel SH. Choline: Needed for normal development of memory. J Am Coll Nutr, 19(5):528S-531S:2000

  9. Gruenwald J, et al. PDR for Herbal Medicines, 2nd ed. Medical Economics, Montvale (NJ), 2000

  10. Null G. The Clinician"s Handbook of Natural Healing. Kensington, New York, 1997

  11. Null G. The Complete Encyclopedia of Natural Healing. Kensington Books, 1998

  12. Dukic-Stefanovic S, Schinzel R, Riederer P, Munch G. AGES in brain ageing: AGE-inhibitors as neuroprotective and anti-dementia drugs? Biogerontology. 2001;2(1):19-34

  13. Werbach MR. Textbook of Nutritional Medicine. Third Line Press, Tarzana (CA), 1999

  14. Smythies JR Halsey JH. Treatment of Parkinson"s disease with l-methionine. South Med J, 77:1577, 1984

  15. Specific nutrients aid in high-performance activity. Nutr Week, June 4, 1994:7

  16. Lamb, variety meats and by-products, brain, raw. NDB No. 17185. USDA National Nutrient Database for Standard Reference, Release 16-1 (2004)

  17. Balch JF, Blach PA. Prescription for Nutritional Healing, 2 nd ed. Avery Publishing Group, Garden City Park (NY), 1997

  18. DeCava JA. Glandular supplements. Nutrition News and Views 1997; 1(3):1-10

  19. Burns D. Growing scientific evidence support glandular therapy. Digest of Chiropractic Economics, Nov/Dec 1987:74-79

  20. Schwartz EF. Glandular therapy. American Chiropractor, Jan/Feb 1983:14-18

  21. Lee R, Hanson W. Protomorphology: The Principles of Cell Auto-Regulation. Lee Foundation for Nutritional Research, Milwaukee, 1947

  22. Dunbar R. Foraging for nature"s balanced diet. New Scientist August 31, 1991:25-28

  23. Lee R. Therapeutic Food Manual, Lee Foundation for Nutritional Research, Milwaukee, circa 1950;14

  24. Lee R. Brain Cytotrophin. Lee Foundation for Nutritional Research, Milwaukee, circa 1950

  25. Profiles in Nutritional Progress. Rubicon Productions, Bakersfield, 1993

  26. Cenacchi T, et al. Cognitive decline in the elderly: a double-blind placebo-controlled multicenter study on the efficacy of phosphatidylserine administration. Aging Clin Exp Res 5:123-133, 1993

  27. Dean W, Morgenthaler J, Fowkes SW. Phosphatidylserine. In Smart Drugs II: The Next Generation. Smart Publications, Petaluma (CA), 1993:75-80

  28. Harrower HR. An Endocrine Handbook. Harrow Laboratory, Glendale, 1939

  29. Nuttail Dr . Blood Immunity and Blood Relationships. Cambridge University Press, London, 1904

  30. Biotechnology in the Feed Industry. Nottingham Press, UK, 1995: 257-267

  31. Riggs K, et al. Relations of vitamin B-12, vitamin B-6, folate, and homocysteine to cognitive performance in the Normative Aging Study. Am J Clin Nutr 63:306-314, 1996

  32. Shils M, Olson J, Shine M, Ross A, eds. Modern Nutrition in Health and Disease, 9th ed. William & Wilkins, Balt.,1999

  33. Solfrizzi V, Panza F, Capurso A. The role of diet in cognitive decline. J Neural Transm. 2003;110(1):95-110

  34. ORAC Test by Brunswick Laboratories, Wareham (MA), February 2006

  35. Sheldon SS, Rorvik D, ed. PDR for Nutritional Supplements, 1 st ed. Medical Economics, Montvale (NJ), 2001

Some of these studies (or citations) may not conform to peer review standards, therefore, the results are not conclusive. Professionals can, and often do, come to different conclusions when reviewing scientific data. None of these statements have been reviewed by the FDA. All products distributed by Doctors" Research, Inc. are nutritional and are not intended for the treatment or prevention of any medical condition.

 

 

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Vegetarian Tryptophan
Vegetarian Tyrosine
Vira-Bac-YST
Vita B-6, B-12, & Folate
  
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Important Note:
The information presented herein by The Natural Path Botanicals is intended for educational purposes only. These statements have not been evaluated by the FDA and are not intended to diagnose, cure, treat or prevent disease. Individual results may vary, and before using any supplements, it is always advisable to consult with your own health care provider.

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