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Vegetarian Adrenal TM

There is no doubt that we live in a high stress society. Not only do we live and work in unnatural environments, our foods are vastly different than they were 150 years ago. Until relatively recently, no human ever consumed synthesized isolated USP vitamins. Should stress vitamin formulas be primarily synthetic substances which can add stress to the body? We think not!

Vegetarian Adrenal is a 100% vegan Food supplement intended to nutritionally support the adrenal glands and help support biochemical imbalances associated with cortisol production. The adrenal glands play a role in energy, stress, mood, and even pain control. The adrenal glands have probably the greatest store of vitamin C in the body. Vegetarian Adrenal is basically Food intended for the adrenal glands (it is not advised if breastfeeding). If additional endocrine support is indicated, consider adding Vegetarian Thyro or Vegetarian Tyrosine.

Carob Pod Ceratonia siliqua is a natural Food source high in the amino acid serine (see L-Serine below) [1]. In addition, research has concluded, "The presence of substances with central benzodiazepine activity in carob extracts seems of great importance in view of the possibility to use carob extract as potential natural products with anxiolytic-sedative effects" [2].

Citrus sinensis contains nearly all of the vitamin C and bioflavonoids in Vegetarian Adrenal. Bioflavonoids are normally yellowish substances that are derivatives of flavones. While some ascorbic acid formulas contain some bioflavonoids, they normally do not have the full complement of them that nature provides. Citrus fruits, for example, contain a variety of truly organic bioflavonoids including flavanone glycosides, naringin, neorioctrin, neohesperidin, hesperiden, flavone glycosides, rhoifolin, luteolin, neodiosnin, flavon aglycones, tetra-o-methylisoscutellaren, sinensetin, isosinensetin, tangeritin, nobiletin, 5-0-desmethylnobiletin. Bioflavonoids from citrus sources have been shown to help normalize cortisol levels [3]. "A common biological alteration in patients with major depression is the activation of the hypothalamic-pituitary-adrenal (HPA) axis, manifested as hypersecretion of adrenocorticotropic hormone (ACTH) and cortisol. The hyperactivity of the HPA axis in depressed patients can be corrected during clinically effective therapy with standard antidepressant drugs such as imipramine, indicating that the HPA axis may be an important target for antidepressant action", and some flavonoids "play an important role in the modulation of HPA axis function. Furthermore, the results support the hypothesis that flavonoids are involved in the antidepressant effects" [4].

Guar gum seed is a water soluble fiber (in the form of a galactomannan), extracted from locust beans. It improves "tolerance to glucose by decreasing absorption", which makes it of value for many [5].

L- Serine is an non-essential amino acid, that along with some others help produce the "enzyme that catalyzes the first step in the conversion of circulating dehydroepiandrosterone (DHEA), pregnenolone or 17alpha-hydroxypregenolone to produce the appropriate, active steroid hormone(s): estradiol, testosterone, progesterone, aldosterone or cortisol respectively" [6]. L-serine is known to help restore compromised adrenal function, as well as helping to reduce elevated cortisol levels.

Lycopene in tomato powder, which is how it is in Vegetarian Adrenal appears to be more bioavailable than that in fresh tomatoes, and tomato powder has (by weight) 26-144 times more lycopene than fresh tomatoes [7]. "Among the common dietary carotenoids lycopene has the highest singlet oxygen quenching capacity in vitro. Other outstanding features are its high concentration in" {the} adrenal gland" [8]. Studies suggest it has a variety of protective effects [7].

Potassium is found in plants [9]. Potassium is the leading intracellular electrolyte and is necessary for electrolyte balance, stimulating aldersterone for the adrenal glands [9]. The late Dr. Bernard Jensen wrote the following about potassium deficiencies, "The mind becomes chaotic, unpredictable, highly imaginative and unorthodox. States of mind alternate between joy and melancholy and even excitability"Potassium Must be Supplied in Food Form" [10] (bolding his).

 Rice bran is a Food source of B vitamins [7], which are often used for stress, anxiety, and adrenal support.

Vitamin B-5 Pantothenate is "the number one adrenal strengthener" [11]. Severe deficiency of vitamin B-5 causes numbness in toes and painful burning in feet, and can cause anemia, skin problems, and adrenal problems [12]. Because of cortisol"s anti-allergy properties this may be why many advise pantothenate for allergies. "Synthetic D-pantothenate...is available as a calcium or sodium salt" [12], and is sold in forms such as sodium D-pantothenate or calcium D-pantothenate or sometime just listed as pantothenic acid [13]. Other synthetic "multivitamin preparations commonly contain its...alcohol derivative, panthenol" [12]. "Dexopanthenol is a synthetic form which is not found naturally" [13]. USP pantothenic acid is made by condensing isobutyraldehyde with formaldehyde [14]. "Pantothenic acid consists of pantoic acid in amide linkage to beta-alanine", but vitamin B-5 is not found that way in nature, pantothenate forms are [15]. The vegetarian foods which are highest in pantothenate are nutritional yeast, brown rice, peanuts, and broccoli [12,13,15]. Nutritional yeast and brown rice supply the vitamin B-5 in Vegetarian Adrenal, and are two of the best natural sources of food pantothenate [12,13].

Vitamin B-6 : "An understanding of the various forms [of vitamin B-6] and quantities of these forms in foods is important in the evaluation of the bioavailability and metabolism of vitamin B-6" [16]. One of the forms that vitamin B-6 exists in is the form "5"0-(beta-D-glycopyransosyl) pyridoxine. To date only plant foods have been found to contain this interesting form of vitamin B-6" [16]. Yeast and rice bran contain more natural food vitamin B-6 than other foods [17]. Reports suggest that food vitamin B-6 is superior to forms [18]. At least one synthetic vitamin B-6 analogue has been found to inhibit natural vitamin B-6 action [19]. Pyridoxine HCL (hydrochloride) which is found in most non-food supplements is made with petroleum ester combined with HCL and processed with formaldehyde [20]. "Disorders treated with (B-6)...include Down"s syndrome, autism, hyperoxaluria, gestational diabetes, carpal tunnel syndrome, depression, and diabetic neuropathy" [12]. Many problems including anemias, premenstrual dysphoric disorder (PMDD), PMS, cardiovascular complaints, confusion, depression, irritability, and certain immune problems have responded to vitamin B-6 [21]. A study of healthy elderly individuals found about 1/3 had marginal vitamin B-6 deficiency [21].

Vitamin C in the human body, is found in the greatest abundance in the adrenal glands, which demonstrates that many aspects of adrenal physiology require vitamin C. Foods generally contain two biologically active forms of vitamin C [12,22,23], yet most synthetic vitamin C only contains isolated ascorbic acid [24,25]. One M.D. writes, "If anything helps you battle the effects of stress, it is vitamin C" [26]; vitamin C "can readily donate electrons to quench a variety of reactive free radical and oxidative species and is easily returned to its reduced state...The vitamin efficiently scavenges hydroxyl, peroxyl, and superoxide radicals, as well as reactive peroxide, singlet oxygen, and hypochlorite species" and protects against lipid and low-density lipoprotein (LDL) peroxidation" [12].

Many people simply take Vegetarian Adrenal as a Food supplement to help them feel better.

Unlike many so-called "natural" formulas, Vegetarian Adrenal is only comprised of foods or food extracts, contains no synthetic USP nutrients or isolated mineral salts, but only contains foods, food complexes, and food concentrates.  Food nutrients are better because they contain important enzymes, peptides, and phyonutrients CRITICAL to the UTILIZATION of vitamins and minerals which are not present in isolated USP nutrients.  Published research has specifically concluded that food vitamins are superior to synthetic/USP vitamins.

Suggested use: 1-4 tablets per day or as recommended by your health care professional.  Adjust usage according to nutritional lifestyle requirements.

No Synthetic Nutrients * No Dairy * No Preservatives


[1] USDA. Carob Powder. USDA National Nutrient Database for Standard Reference, Release 18 (2005)

[2] Avallone R, Cosenza F, Farina F, Baraldi C, Baraldi M. Extraction and purification from Ceratonia siliqua of compounds acting on central and peripheral benzodiazepine receptors. Fitoterapia. 2002;73(5):390-396

[3] Lee YS, Lorenzo BJ, Koufis T, Reidenberg MM.

Grapefruit juice and its flavonoids inhibit 11 beta-hydroxysteroid dehydrogenase. Clin Pharmacol Ther. 1996;59(1):62-71

[4] Butterweck V, Hegger M, Winterhoff H. Flavonoids of St. John's Wort reduce HPA axis function in the rat. Planta Med. 2004;70(10):1008-1011

[5] Trinick TR, Laker MF, Johnston DG, Keir M, Buchanan KD, Alberti KG. Effect of guar on second-meal glucose tolerance in normal man. Clin Sci (Lond). 1986;71(1):49-55

[6] Thomas JL, Duax WL, Addlagatta A, Scaccia LA, Frizzell KA, Carloni SB. Serine 124 completes the Tyr, Lys and Ser triad responsible for the catalysis of human type 1 3beta-hydroxysteroid dehydrogenase. J Mol Endocrinol. 2004;33(1):253-261

[7] Sheldon S, Rorvik D, eds. PDR for Nutritional Supplements. Medical Economics, Montvale (NJ), 2001

[8] Gerster H. The potential role of lycopene for human health. J Am Coll Nutr. 1997;16(2):109-126

[9] Whitney EN, Hamilton EMN. Understanding Nutrition, 4ed. West Publishing, New York, 1987

[10] Jensen B. The Chemistry of Man. Bernard Jensen Enterprises, Escondido (CA), 1983

[11] Null G. The Complete Encyclopedia of Natural Health. Kensington Books, NY, 1998

[12] Shils ME, Olson JA, Shike M. Modern Nutrition in Health and Disease, 9th ed. Williams & Wilkins, Balt., 1999

[13] Hendler S, Rorvik D, editors. PDR for Nutritional Supplements. Medical Economics, Montvale (NJ), 2001

[14] Vitamin-Mineral Manufacturing Guide Nutrient Empowerment, volume 1. Nutrition Resource, Lakeport (CA), 1986

[15] Plesofsky-Vig N. Pantothenic acid and Coenzyme A. In Modern Nutrition in Health and Disease, 8th ed. Lea & Febiger, Phil.,1994:395-401

[16] Leklem JE. Vitamin B6. In Modern Nutrition in Health and Disease, 8th ed. Lea & Febiger, Phil.,1994:383-394

[17] Ensminger AH, Ensminger ME, Konlade JE, Robson JRK. Food & Nutrition Encyclopedia, 2nd ed. CRC Press, New York, 1993

[18] Thiel R. Natural vitamins may be superior to synthetic ones. Medical Hypotheses, 2000; 55(6):461-469

[19] Mervyn L. The B Vitamins. Thorsons, Wellingborough ( UK), 1981

[20] Vitamin-Mineral Manufacturing Guide Nutrient Empowerment, volume 1. Nutrition Resource, Lakeport (CA), 1986

[21] Hendler SS, Rorvik D, eds. PDR for Nutritional Supplements. Medical Economics, Montvale (NJ), 2001

[22] Levine, M, et al. Vitamin C. In Present Knowledge in Nutrition, 7th ed. ILSI Press, Washington, 1996:146-159

[23] Vanderslice JT, Higgs DJ. Vitamin C content of foods: sample variability. Am J Clin Nutr, 1991;54(Supp 6):1323S-1327S

[24] The United States Pharmacopeial Convention. USAN and USP Dictionary of Drug Names. Mack Printing, Easton (PA),1986

[25] Mangels AR, et al. The bioavailability to humans of ascorbic acid from oranges, orange juice and cooked broccoli is similar to that of synthetic ascorbic acid. J Nutr, 1993;123(6):1054-1061

[26] Understanding Vitamins and Minerals. Rodale Press, Emmaus (PA), 1984

Some of these studies (or citations) may not conform to peer review standards (though most do). Therefore, the results are not conclusive. Professionals can, and often do, come to different conclusions when reviewing scientific data. None of these statements have been reviewed by the FDA. All products distributed by Doctors" Research, Inc. are nutritional and are not intended for the treatment or prevention of any medical condition.



Vegetarian Adrenal Video

Advanced Joint Complex
Aller-Lung Support
Arginase Bladder
B Stress Complex
C Complex
Cal-Mag Complex
Calcium Complex

Complete Ear Health
Complete Eye Health
Smell & Taste
D Complex
GB Support
Green Vegetable Alkalyzer
Hematic Formula
Herbal Antioxidant
High Stress Adrenal
Inositol Complex
Le Feminine Advantage
Magnesium Complex
Metabolic Thyro

Omega 3 / EPA / DHA
Restful Mind Support
Selenium E Complex
Serious Brain Enhancer
Simply Glandulars
Vegetarian Adrenal
Vegetarian Thyro
Vegetarian Tryptophan
Vegetarian Tyrosine
Vita B-6, B-12, & Folate
Vitamin Mineral
Wheat Germ Oil
Zinc Complex



Important Note:
The information presented herein by The Natural Path Botanicals is intended for educational purposes only. These statements have not been evaluated by the FDA and are not intended to diagnose, cure, treat or prevent disease. Individual results may vary, and before using any supplements, it is always advisable to consult with your own health care provider.

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