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High Stress Adrenal

There is no doubt that we live in a high stress society. Not only do we live and work in unnatural environments, our foods are vastly different than they were 150 years ago. Until relatively recently, no human ever consumed synthesized isolated USP vitamins. Should stress vitamin formulas be primarily synthetic substances which can add stresses to the body? We think not!  

High Stress Adrenal is a 100% Food supplement that is intended to supply nutrients, glandulars, and herbs needed to maintain and support optimal adrenal health. The adrenal glands play a role in energy, stress, mood, immune support, and pain management. High Stress Adrenal contains many of the substances produced by, or naturally in, those glands including peptides, hormone precursors, and enzymes. Additionally, it includes l-tyrosine, food B vitamins, food vitamin C, and herbs to support healthy adrenal function.  Food nutrients are natural for the body and are preferred for stress handling for humans:

Food Nutrients Are Not the Same as USP!

Food nutrients are not structurally, nor in most cases chemically, the same as USP isolates. Electron microscopy reveals that isolated USP form vitamins have a crystalline appearance whereas Food nutrients have more of a rounded appearance. Food nutrients also appear smaller than USP form vitamins and minerals. Nutrition scientists understand that smaller particle size improves bioavailability [1], "Small particles greatly enhances digestion in the small intestine, because the smaller particles of food have a larger ratio of surface to mass" [2] (the main function of digestion is to get Food particles small enough to be absorbed by intestinal villi [1,2]). Food nutrients do look different to the human eye.

Food Vitamin C

Regular 'Natural' Ascorbic Acid

Synthetic "nutrients" do not do all the functions that natural ones do[3], so why would anyone want to take them?

Natural vs. Synthetic Vitamins and Stress

"Synthetic thiamin is usually marketed as thiamin hydrochloride or thiamin mononitrate" [5] and is a "coal tar derivative" [6] (most synthetic vitamins are petroleum derivatives). No thiamin hydrochloride or thiamin mononitrate is naturally found in any Food (thiamin pyrophosphate is the most common Food form of vitamin B-1 [2]). Other synthetic B vitamin forms include pyridoxine hydrochloride, folic acid, pantothenic acid, and cyanocobalamin--these are all crystalline in structure whereas B vitamins in Food are never crystalline. Research shows that the bioavailability of Food nutrients is greater than that of isolated USP vitamins [7-9]. Why should anyone take large amounts of cheap synthetic USP imitation vitamins (even if the labels say "natural") which themselves can add stresses to the body?

B vitamins and certain herbs have been shown to help reduce stress (e.g. B5-pantothenate is even known as the "anti-stress vitamin") [2,10,11]. Natural Food B-complex vitamins (B1, B2, B3, B5, B6, B8-inositol, B9-folate, B12) are necessary for energy metabolism and inadequate amounts can lead to pernicious anemia, low hemoglobin counts, skin problems, nervous system problems, and even serious mental problems [2]. Vitamin C "can readily donate electrons to quench a variety of reactive free radical and oxidative species and is easily returned to its reduced state...The vitamin efficiently scavenges hydroxyl, peroxyl, and superoxide radicals, as well as reactive peroxide, singlet oxygen, and hypochlorite species" and protects against lipid and low-density lipoprotein (LDL) peroxidation" [2].

How Much Better are Food Vitamins?

Doctors" Research Food

Compared to USP Vitamin/Mineral Salt



Vitamin B-1, Thiamin

Not a different chemical compound

Vitamin B-5, Pantothenate

Not a different chemical compound

Vitamin B-6

Not a different chemical compound

Vitamin B-9, Folate

More utilizable above 266mcg (RDI is 400mcg) [3]

Vitamin C

Up to 15.6 times antioxidant effect [4]


Better absorbed and retained


Better absorption

Synthetic "nutrients" do not do all the functions that natural ones do [1,2], so why would anyone want to take them?

Other Nutrients In High Stress Adrenal

Siberian ginseng is considered to be an adaptogen-which is a Food that increases stress-handling abilities and improves well-being [7,12]. "Siberian ginseng root contains bitter compounds that help the body quickly respond to stress. These compounds increase the production of DNA, RNA and proteins essential to all life processes. They stimulate the adrenal" [12]. "The main active component in ginseng consists of ginsenosides, a diverse group of steroidal saponins. There are twenty-five ginsenosides that have been separated...It is used internally for fatigue and debility, and for a decrease capacity for work and concentration" [7]. It has been found to reduce age-related cognitive impairment, have antineoplastic effects, antioxidant effects, antiplatelet effects, antiviral effects, and be beneficial in blood sugar regulation [7]. It is also used for anxiety [7]. Kelp is Foodthat supplies trace minerals [12].

The hypothalamus is the body"s master endocrine gland. It can increase tranquility [13]. The adrenal glands help the body deal with stress through the production of hormones including epinephrine and norepinephrine [13], but high stress weakens the adrenal glands [14] (note: all glandulars in B Stress Complex are bovine New Zealand source). L-tyrosine is an amino acid used in the production of adrenal and thyroid hormones [13] and may "improve vigilance and lessen anxiety" [15]. Whereas, S.O.D. "is one of the most important enzymes that functions as a cellular antioxidant...The absence of this enzyme is lethal" [2]. Studies show that antioxidant S.O.D. appears to have protective effects for the heart, lungs, joints, kidneys, liver, muscles, and skin [16].

High Stress Adrenal is often, simply an excellent option for helping in our high stress world.


High Stress Adrenal naturally contains carbohydrates, lipids, proteins (including all ten essential amino acids), iodine, and truly organic bioflavonoids as found in specially grown, enzymatically processed Saccharomyces cerevisiae, L-tyrosine, Mixed citrus fruit, New Zealand bovine glandular concentrates, Acerola cherryMalpighia glabra, Eleutherococcus senticosus (formerly known as Siberian ginseng), and Kelp thallusAscophyllum nodesumall the nutrients shown above are contained in these foods. Unlike many so-called "natural" formulas, High Stress Adrenal is only comprised of foods, contains no synthetic USP nutrients or isolated mineral salts, but only contains foods, food complexes, and food concentrates.

Numerous university studies have concluded that supplements containing food nutrients are better than USP isolates. Food nutrients are better because they contain important enzymes, peptides, and phytonutrients CRITICAL to the UTILIZATION of vitamins and minerals which are not present in isolated USP nutrients. Published research has concluded that food vitamins are superior synthetic/USP vitamins.

Suggested use: 1-6 tablets per day or as recommended by your health care professional. Adjust usage according to nutritional lifestyle requirements.


[1] Jenkins DJA, Wolever TMS, and Jenkins AL. Diet Factors Affecting Nutrient Absorption and Metabolism. In Modern Nutrition in Health and Disease, 8th ed. Lea and Febiger, Phil.:583-602, 1994

[2] Shils ME, Olson JA, Shike J. In Modern Nutrition in Health and Disease, 8th ed. Lea and Febiger, Phil., 1994; 9th ed. Williams & Wilkins, Balt., 1999

[3] DeCava JA. The Real Truth About Vitamins & Antioxidants. A Printery, Centerfield (MA), 1997

[4] Macrae R, Robson RK, Sadler MJ. Encyclopedia of Food Science and Nutrition. Academic Press, NY, 1993

[5] Haynes W. Chemical Trade Names and Commercial Synonyms, 2nd ed. Van Nostrand Co., New York, 1955

[6] Understanding Vitamins and Minerals. Rodale Press, Emmaus (PA), 1984

[7] PDR for Herbal Medicine, 2nd ed. Medical Economics, Montvale (NJ), 2000

[8] Ha SW. Rabbit study comparing yeast and isolated B vitamins (as described in Murray RP. Natural vs. Synthetic. Mark R. Anderson, 1995, p:A3). Ann Rev Physiol,1941; 3:259-282

[9] Thiel R. Natural vitamins may be superior to synthetic ones. Med Hypo.2000;55(6):461-469

[10] Lucock M. Is folic acid the ultimate functional food component for disease prevention? BMJ, 2004;328:211-214

[11] Williams D. ORAC values for fruits and vegetables. Alternatives, 1999;7(22):171

[12] Pederson M. Nutritional Herbology: A Reference Guide to Herbs, 3rd ed. Whitman Books, Warsaw (IN), 1998

[13] Guyton AG, Hall JE. Textbook of Medical Physiology, 9th ed. W.B. Saunders Co., Phil., 1996

[14] Amberson JB, Gray GF. Adrenal pathology. In Adrenal Disorders. Thieme Medical Publishers: New York; 1983:13-36

[15] Specific nutrients aid in high-performance activity. Nutr Week, June 4, 1994:7

[16] Null G. The Clinician"s Handbook of Natural Healing, Kensington, NY, 1998


Some of these studies (or citations) may not conform to peer review standards. Therefore, the results are not conclusive. Professionals can, and often do, come to different conclusions when reviewing scientific data. None of these statements have been reviewed by the FDA. All products distributed by Doctors" Research, Inc. are nutritional and are not intended for the treatment or prevention of any medical condition.


High Stress Adrenal Video


Advanced Joint Complex
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B Stress Complex
C Complex
Cal-Mag Complex
Calcium Complex

Complete Ear Health
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D Complex
Green Vegetable Alkalyzer
Hematic Formula
High Stress Adrenal
Le Feminine Advantage
Magnesium Complex
Metabolic Thyro
Restful Mind Support

Selenium E Complex
Serious Brain Enhancer
Simply Glandulars
Vegetarian Adrenal
Vegetarian Thyro
Vita B-6, B-12, & Folate
Vitamin Mineral
Zinc Complex



Important Note:
The information presented herein by The Natural Path Botanicals is intended for educational purposes only. These statements have not been evaluated by the FDA and are not intended to diagnose, cure, treat or prevent disease. Individual results may vary, and before using any supplements, it is always advisable to consult with your own health care provider.

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